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  2. Helicobacter pylori eradication protocols - Wikipedia

    en.wikipedia.org/wiki/Helicobacter_pylori...

    The success of H. pylori cure depends on the type and duration of therapy, patient compliance and bacterial factors such as antibiotic resistance. Patients most often fail to respond to initial H. pylori eradication therapy because of noncompliance or antibiotic resistance. Patients should be queried about any side effects, missed doses, and ...

  3. Helicobacter pylori - Wikipedia

    en.wikipedia.org/wiki/Helicobacter_pylori

    H. pylori is able to adhere to the surface of the phagocytes and impede their action. This is responded to by the phagocyte in the generation and release of oxygen metabolites into the surrounding space. H. pylori can survive this response by the activity of catalase at its attachment to the phagocytic cell surface. Catalase decomposes hydrogen ...

  4. Peptic ulcer disease - Wikipedia

    en.wikipedia.org/wiki/Peptic_ulcer_disease

    Once the diagnosis of H. pylori is confirmed, the first-line treatment would be a triple regimen in which pantoprazole and clarithromycin are combined with either amoxicillin or metronidazole. This treatment regimen can be given for 7–14 days. However, its effectiveness in eradicating H. pylori has been reducing from 90% to 70%. However, the ...

  5. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    These infections can include Helicobacter pylori due to this species not favouring an acid environment, leading to an increased risk of ulcers and gastric cancer risk in genetically susceptible patients. [50] PPI use in people who have received attempted H. pylori eradication may also be associated with an increased risk of gastric cancer. [51]

  6. Gastritis - Wikipedia

    en.wikipedia.org/wiki/Gastritis

    Gastritis caused by H. pylori infection is termed Helicobacter pylori induced gastritis, and listed as a disease in ICD11. [6] [7] More than 80% of individuals infected with the bacterium are asymptomatic and it has been postulated that it may play an important role in the natural stomach ecology. [17]

  7. Omeprazole/amoxicillin/rifabutin - Wikipedia

    en.wikipedia.org/wiki/Omeprazole/amoxicillin/...

    Clinical trial number NCT03198507 for "ERADICATE Hp2 - Treating Helicobacter Pylori With RHB-105 Compared to Active Comparator (ERADICATE Hp2)" at ClinicalTrials.gov Clinical trial number NCT01980095 for "ERADICATE Hp - Treating Helicobacter Pylori With RHB-105 (ERADICATE Hp)" at ClinicalTrials.gov

  8. Urea breath test - Wikipedia

    en.wikipedia.org/wiki/Urea_breath_test

    Patients swallow urea labelled with an uncommon isotope, either radioactive carbon-14 (nowadays preferred in many countries) or non-radioactive carbon-13.In the subsequent 10–30 minutes, the detection of isotope-labelled carbon dioxide in exhaled breath indicates that the urea was split; this indicates that urease (the enzyme that H. pylori uses to metabolize urea to produce ammonia) is ...

  9. Clarithromycin - Wikipedia

    en.wikipedia.org/wiki/Clarithromycin

    Clarithromycin, sold under the brand name Biaxin among others, is an antibiotic used to treat various bacterial infections. [3] This includes strep throat, pneumonia, skin infections, H. pylori infection, and Lyme disease, among others. [3]

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