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M8201/2 Cribiform carcinoma in situ (C50._) Ductal carcinoma in situ, cribiform type; M8201/3 Cribiform carcinoma, NOS Ductal carcinoma, cribiform type; M8202/0 Microcystic adenoma (C25._) M8204/0 Lactating adenoma; M8210/0 Adenomatous polyp, NOS Polypoid adenoma; M8210/2 Adenocarcinoma in situ in adenomatous polyp Adenocarcinoma in situ in ...
Dysplasia is the earliest form of precancerous lesion recognizable in a biopsy. Dysplasia can be low-grade or high-grade. High-grade dysplasia may also be referred to as carcinoma in situ. Invasive carcinoma, usually simply called cancer, has the potential to invade and spread to surrounding tissues and structures, and may eventually be lethal.
In HGPIN, the basal cell layer is disrupted but present. PIN is primarily found in the peripheral zone of the prostate (75-80%), rarely in the transition zone (10-15%) and very rarely in the central zone (5%), a distribution that parallels the zonal distribution for prostate carcinoma. [7]
Potentially-malignant neoplasms include carcinoma in situ. They are localised, and do not invade and destroy but in time, may transform into cancer. Malignant neoplasms are commonly called cancer. They invade and destroy the surrounding tissue, may form metastases and, if untreated or unresponsive to treatment, will generally prove fatal.
The term dysplasia is typically used when the cellular abnormality is restricted to the originating tissue, as in the case of an early, in-situ neoplasm. [ citation needed ] Dysplasia, in which cell maturation and differentiation are delayed, can be contrasted with metaplasia , in which cells of one mature, differentiated type are replaced by ...
Germ cell neoplasia in situ (GCNIS) represents the precursor lesion for many types of testicular germ cell tumors. [ 1 ] The term GCNIS was introduced with the 2016 edition of the WHO classification of urological tumours. [ 1 ]
A histopathologic diagnosis of prostate cancer is the discernment of whether there is a cancer in the prostate, as well as specifying any subdiagnosis of prostate cancer if possible. The histopathologic subdiagnosis of prostate cancer has implications for the possibility and methodology of any subsequent Gleason scoring . [ 1 ]
Prostate cancer is the most diagnosed cancer in men in over half of the world's countries, and the leading cause of cancer death in men in around a quarter of countries. [92] Prostate cancer is rare in those under 40 years old, [93] and most cases occur in those over 60 years, [2] with the average person diagnosed at 67. [94]