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In humans, the circulatory system is different before and after birth. The fetal circulation is composed of the placenta, umbilical blood vessels encapsulated by the umbilical cord, heart and systemic blood vessels. A major difference between the fetal circulation and postnatal circulation is that the lungs are not used during the fetal stage ...
Persistent fetal circulation is a condition caused by a failure in the systemic circulation and pulmonary circulation to convert from the antenatal circulation pattern to the "normal" pattern. Infants experience a high mean arterial pulmonary artery pressure and a high afterload at the right ventricle.
Fetal circulation; the umbilical vein is the large, ... and can often be performed until 2 weeks after birth (when the arteries start to decay too much). [7]
The "E" series of prostaglandins are responsible for maintaining the openness of the ductus arteriosus (by dilation of vascular smooth muscle) throughout the fetal period. [3] Prostaglandin E2 (PGE 2 ), produced by both the placenta and the DA itself, is the most potent of the E prostaglandins, but prostaglandin E1 (PGE 1 ) also has a role in ...
In placental mammals, the umbilical cord (also called the navel string, [1] birth cord or funiculus umbilicalis) is a conduit between the developing embryo or fetus and the placenta. During prenatal development , the umbilical cord is physiologically and genetically part of the fetus and (in humans) normally contains two arteries (the umbilical ...
The unpaired umbilical vein carries oxygen and nutrient rich blood derived from fetal-maternal blood exchange at the chorionic villi.More than two-thirds of fetal hepatic circulation is via the main portal vein, while the remainder is shunted from the left portal vein via the ductus venosus to the inferior vena cava, eventually being delivered to the fetal right atrium.
Human embryo at approximately 30 days, showing development of various structures including the yolk sac.From Gray's anatomy. Vasculogenesis is the formation of early vasculature, which is laid down by genetic factors. [7]
The pathway of fetal umbilical venous flow is umbilical vein left portal vein ductus venosus inferior vena cava eventually right atrium.. This anatomic course is important to recall when assessing the success of neonatal umbilical venous catheterization, as failure to cannulate through the ductus venosus results in malpositioned hepatic catheterization via the left or right portal veins.