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Nitazoxanide is an effective first-line treatment for infection by Blastocystis species [11] [12] and is indicated for the treatment of infection by Cryptosporidium parvum or Giardia lamblia in immunocompetent adults and children. [1]
Blastocystis cysts have been shown to be resistant to chlorination as a treatment method [42] and are among the most resistant cysts to ozone treatment. [ 43 ] Contaminated Food : Contamination of leafy vegetables has been implicated as a potential source for transmission of Blastocystis infection, as well as other gastrointestinal protozoa. [ 44 ]
Blastocystis hominis is a single-celled eukaryotic organism that inhabits the gastrointestinal tract of humans and various animals. [1] This stramenopile exhibits significant genetic diversity and has become an organism of increasing scientific interest due to its widespread distribution and controversial role in human health. [ 2 ]
Blastocystis is a genus of single-celled parasites belonging to the Stramenopiles that includes algae, diatoms, and water molds.There are several species, living in the gastrointestinal tracts of species as diverse as humans, farm animals, birds, rodents, reptiles, amphibians, fish, and cockroaches. [2]
Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [10] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [10] It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. [10]
This antibiotic is not recommended for children and 75 and up of age: Inactivates enolpyruvyl transferase, thereby blocking cell wall synthesis Fusidic acid: Fucidin: Metronidazole: Flagyl: Infections caused by anaerobic bacteria; also amoebiasis, trichomoniasis, giardiasis: Discolored urine, headache, metallic taste, nausea; alcohol is ...
Treatment Metronidazole for the invasive trophozoites PLUS a lumenal amoebicide for those still in the intestine. Paromomycin (Humatin) is the luminal drug of choice, since Diloxanide furoate (Furamide) is not commercially available in the United States or Canada (being available only from the Centers for Disease Control and Prevention).
[54] [55] [56] One study found that 43% of IBS patients were infected with Blastocystis versus 7% of controls. [49] An additional study found that many IBS patients from whom Blastocystis could not be identified showed a strong antibody reaction to the organism, which is a type of test used to diagnose certain difficult-to-detect infections. [52]
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