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  2. Medication package insert - Wikipedia

    en.wikipedia.org/wiki/Medication_package_insert

    Physicians legally can and often do prescribe medicines for purposes not listed in this section (so-called "off-label uses"). Contraindications - lists situations in which the medication should not be used, for example in patients with other medical conditions such as kidney problems or allergies

  3. Benzocaine - Wikipedia

    en.wikipedia.org/wiki/Benzocaine

    Benzocaine, sold under the brand name Orajel amongst others, is a local anesthetic, belonging to the amino ester drug class, commonly used as a topical painkiller or in cough drops. It is the active ingredient in many over-the-counter anesthetic ointments such as products for oral ulcers. It is combined with antipyrine to form A/B ear drops.

  4. Boxed warning - Wikipedia

    en.wikipedia.org/wiki/Boxed_warning

    In the United States, a boxed warning (sometimes "black box warning", colloquially) is a type of warning that appears near the beginning of the package insert for certain prescription drugs, so called because the U.S. Food and Drug Administration specifies that it is formatted with a 'box' or border around the text [1] to emphasize its ...

  5. Physicians' Desk Reference - Wikipedia

    en.wikipedia.org/wiki/Physicians'_Desk_Reference

    The book was distributed for free to all licensed medical doctors in America; only drugs which drug manufacturers paid to appear, appeared in the PDR, and no generic drugs were listed. The 71st Edition, published in 2017, was the final hardcover edition, weighed in at 4.6 pounds (2.1 kg) and contained information on over 1,000 drugs. [ 1 ]

  6. Brivudine - Wikipedia

    en.wikipedia.org/wiki/Brivudine

    The drug is contraindicated in patients undergoing immunosuppression (for example because of an organ transplant) or cancer therapy, especially with fluorouracil (5-FU) and chemically related (pro)drugs such as capecitabine and tegafur, as well as the antimycotic drug flucytosine, which is also related to 5-FU.

  7. Auxiliary label - Wikipedia

    en.wikipedia.org/wiki/Auxiliary_Label

    Examples of auxiliary labels placed on prescriptions. An auxiliary label (also called cautionary and advisory label or prescription drug warning label) is a label added on to a dispensed medication package by a pharmacist in addition to the usual prescription label.

  8. Contraindication - Wikipedia

    en.wikipedia.org/wiki/Contraindication

    In medicine, a contraindication is a condition (a situation or factor) that serves as a reason not to take a certain medical treatment due to the harm that it would cause the patient. [ 1 ] [ 2 ] Contraindication is the opposite of indication , which is a reason to use a certain treatment.

  9. Adverse effect - Wikipedia

    en.wikipedia.org/wiki/Adverse_effect

    Adverse effects, like therapeutic effects of drugs, are a function of dosage or drug levels at the target organs, so they may be avoided or decreased by means of careful and precise pharmacokinetics, the change of drug levels in the organism in function of time after administration. Adverse effects may also be caused by drug interaction. This ...

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