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[11] [12] Praziquantel is also effective against Echinococcus multilocularis. [11] Schistosomiasis caused by trematodes of the genus Schistosoma: [13] As of 2005, praziquantel is the primary treatment for human schistosomiasis, for which it is usually effective in a single dose. [14] Clonorchiasis brought on by the Chinese liver fluke ...
Praziquantel, however, is often the preferred treatment. [2] It is given by mouth and used as a single dose. [2] Common side effects include sleepiness, headache, nausea, diarrhea, and reddish urine. [1] It is typically not recommended during pregnancy, if possible. [1] Seizures may occur and therefore caution is recommended in people with ...
Praziquantel has some side effects but they are generally relatively mild and transient and a review of evidence shows it overall a well-tolerated drug. Possible side effects include abdominal pain , allergy , diarrhea , headache , liver problems , nausea or vomiting , exacerbation of porphyries , pruritus , rash , somnolence , vertigo , or ...
Post-treatment monitoring Osteopontin (OPN) is a promising tool for monitoring praziquantel efficacy and post-treatment fibrosis regression as (OPN) expression is modulated by S. mansoni egg antigens and its levels correlate with the severity of schistosomiasis fibrosis and portal hypertension in mice and humans. Praziquantel pharmacotherapy ...
Praziquantel – effective against flatworms (e.g., tapeworms and schistosoma) Octadepsipeptides (e.g. Emodepside) – effective against a variety of gastrointestinal helminths; Monepantel (aminoacetonitrile class) – effective against a variety of nematodes including those resistant to other anthelmintic classes
Arpraziquantel ((R)-praziquantel) is the eutomer (the biologically active enantiomer) of praziquantel, and is a medication which is currently under investigation for the treatment of schistosomiasis in young children since it has less side effects than the usual racemic mixture formulation of praziquantel.
The Prescribing Information follows one of two formats: "physician labeling rule" format or "old" (non-PLR) format. For "old" format labeling a "product title" may be listed first and may include the proprietary name (if any), the nonproprietary name, dosage form(s), and other information about the product. The other sections are as follows:
Some work in Michigan suggests that administering praziquantel to hatchling waterfowl can reduce local swimmer's itch rates in humans. [15] Work on schistosomiasis showed that water-resistant topical applications of the common insect repellent DEET prevented schistosomes from penetrating the skin of mice. [16]
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