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The lips are pulled back by the dry skin . [13] Joints sometimes lack movement and may be below the normal size. Hypoplasia is sometimes found in the fingers. Polydactyly has been found on occasion. The fish mouth appearance, mouth breathing, and xerostomia place affected individuals at extremely high risk for developing rampant dental decay. [14]
Plantar fascial fibromatosis, also known as Ledderhose's disease, Morbus Ledderhose, and plantar fibromatosis, is a relatively uncommon [2] non-malignant thickening of the feet's deep connective tissue, or fascia. In the beginning, where nodules start growing in the fascia of the foot, the disease is minor.
The hands and feet usually are the first to show signs of the disease but the disease can advance to other parts of the body. Signs of the disease include thickening of the skin, on hands and soles of feet, which can turn red in color. [6] There currently is no cure and treatment is limited, but Acitretin can be used in severe cases. [7]
Pachyonychia congenita is a rare disorder with an unknown prevalence. As of 2018, the International PC Research Registry has identified approximately 774 individuals with the disease, but prevalence is estimated to be 5,000–10,000 worldwide. [1] [7] The disease affects both males and females.
Epidermolytic hyperkeratosis (also known as "Bullous congenital ichthyosiform erythroderma," [7] "Bullous ichthyosiform erythroderma," [8]: 482 or "bullous congenital ichthyosiform erythroderma of Brocq" [9]) is a rare skin disease in the ichthyosis family, affecting around 1 in 250,000 people.
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Often there is a distinction made between conditions of the dorsal skin and plantar skin. Common examples include callus thickened skin, fungal infections of the skin (athlete's foot) or nails (onychomycosis), viral infection of verrucae, and ingrowing toenails that may cause bacterial nail infections .
13-year-old Lalit Patidar from central India was given the nickname ''wolf boy'' after the effects of a rare condition, known as hypertrichosis, caused him to grow hair all over his face ...