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Sulfinpyrazone is a uricosuric medication used to treat gout. It also sometimes is used to reduce platelet aggregation by inhibiting degranulation of platelets which reduces the release of ADP and thromboxane. Like other uricosurics, sulfinpyrazone works by competitively inhibiting uric acid reabsorption in the proximal tubule of the kidney.
Febuxostat, sold under the brand name Uloric among others, is a medication used long-term to treat gout due to high uric acid levels. [7] It is generally recommended only for people who cannot take allopurinol. [8] [9] It is taken by mouth. [7] Common side effects include liver problems, nausea, joint pain, and a rash. [7]
The NSAID diclofenac has an antiuricosuric action, which may be partly responsible for the extraordinary toxicity of this drug in vultures. [6] Pyrazinamide, a drug indicated only for treatment of tuberculosis, is a potent antiuricosuric [7] and, as a consequence, has an off-label use in the diagnosis of causes of abnormal uric acid clearance. [8]
A couple examples include cyclosporine, an immunosuppressant drug, and diuretics. Lastly, dietary factors also increase gout risk. Specifically, eating lots of purine-rich foods can raise your ...
The post Managing Out-of-Control Chronic Gout: Going Beyond Oral Treatments appeared first on Reader's Digest. Skip to main content. 24/7 Help. For premium support please call: 800 ...
Lesinurad (brand name Zurampic) is a urate transporter inhibitor for treating high blood uric acid levels associated with gout. [2] It is recommended only as an adjuvant with either allopurinol or febuxostat when these medications are not sufficient.
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