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Uremia is the condition of having high levels of urea in the blood. Urea is one of the primary components of urine.It can be defined as an excess in the blood of amino acid and protein metabolism end products, such as urea and creatinine, which would normally be excreted in the urine.
Children are more commonly affected, but most children recover without permanent damage to their health, although some children may have serious and sometimes life-threatening complications. [6] Adults, especially the elderly, may show a more complicated presentation. [2] [6] Complications may include neurological problems and heart failure. [1]
Renal azotemia (acute kidney failure) typically leads to uremia. It is an intrinsic disease of the kidney, generally the result of kidney parenchymal damage. Causes include kidney failure, glomerulonephritis, acute tubular necrosis, or other kidney disease. [3] The BUN:Cr in renal azotemia is less than 15.
Atypical hemolytic uremic syndrome (aHUS), also known as complement-mediated hemolytic uremic syndrome (not to be confused with hemolytic–uremic syndrome), is an extremely rare, life-threatening, progressive disease that frequently has a genetic component. In most cases, it can be effectively controlled by interruption of the complement cascade.
The doctor can look for potential underlying causes, including dementia, medication effects, or environmental factors, Elhelou says. From there, they can suggest effective ways to help you manage ...
Acute kidney injury (AKI), previously called acute renal failure (ARF), [12] [13] is a rapidly progressive loss of renal function, [14] generally characterized by oliguria (decreased urine production, quantified as less than 400 mL per day in adults, [15] less than 0.5 mL/kg/h in children or less than 1 mL/kg/h in infants); and fluid and ...
Ravulizumab, sold under the brand name Ultomiris, is a humanized monoclonal antibody complement inhibitor medication designed for the treatment of paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome. It is designed to bind to and prevent the activation of Complement component 5 (C5). [8] [7]
In Psychology, confusion is the quality or emotional state of being bewildered or unclear. The term "acute mental confusion" [ 1 ] is often used interchangeably with delirium [ 2 ] in the International Statistical Classification of Diseases and Related Health Problems and the Medical Subject Headings publications to describe the pathology .