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α-Ketoglutaric acid is an organic compound with the formula H 2 CC(O)(CH 2) 2 CO 2 H). A white, nontoxic solid, it is a common dicarboxylic acid. Relevant to its biological roles, it exists in water as its conjugate base α-ketoglutarate. It is also classified as a 2-ketocarboxylic acid. β-Ketoglutaric acid is an isomer. "Ketoglutaric acid ...
Ketoglutaric acid (disambiguation) alpha-Ketoglutaric acid; Acetonedicarboxylic acid (beta-Ketoglutaric acid) This page was last edited on 10 August 2019, at 05:06 ...
Ketoglutaric acid or oxoglutaric acid, or its conjugate base, the carboxylate ketoglutarate or oxoglutarate, may refer to the following chemical compounds: α-Ketoglutaric acid, an intermediate in the citric acid cycle; β-Ketoglutaric acid (acetonedicarboxylic acid or 3-oxoglutaric acid)
alpha-ketoglutaric acid, a 5-carbon ketoacid derived from glutamic acid. Alpha-ketoglutarate participates in cell signaling by functioning as a coenzyme. [6] It is commonly used in transamination reactions. Beta-keto acids, beta-ketoacids, or 3-oxoacids, such as acetoacetic acid, have
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However, at the basic pH levels (i.e., pH>7) in virtually all animal tissues, α-ketoglutaric acid and itaconic acid exit almost exclusively as α-ketoglutarate and itaconate, i.e., with their carboxy residues being negatively charged (notated as - CO 2), because they are not bound to H + (see Conjugate acid-base theory). It is α-ketoglutarate ...
Acetonedicarboxylic acid, 3-oxoglutaric acid or β-ketoglutaric acid is a simple dicarboxylic acid with the formula O=C(CH 2 CO 2 H) 2. β-Ketoglutarate does not have the biological activity exhibited by α-ketoglutarate. [2]