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Dabrafenib acts as an inhibitor of the associated enzyme B-Raf, which plays a role in the regulation of cell growth. The most common side effects include papilloma (warts), headache, nausea, vomiting, hyperkeratosis (thickening and toughening of the skin), hair loss, rash, joint pain, fever and tiredness. [3]
The most common side effects include rash, diarrhea, tiredness, peripheral edema (swelling, especially of ankles and feet), nausea and acneiform dermatitis (acne-like inflammation of the skin). [5] When taken in combination with dabrafenib the most common side effects include fever, tiredness, nausea, chills, headache, diarrhea, vomiting, joint ...
Companies are not only focusing on improving the efficacy of BRAF inhibitors but also on reducing side effects and improving patient outcomes through combination regimens that include MEK inhibitors. The approval of combination therapies has set new standards in treatment, offering superior efficacy compared to BRAF inhibitor monotherapy.
1.2 Side effects. 2 History. 3 Society and culture. ... trial results compared vemurafenib with the combination of dabrafenib and trametinib for metastatic melanoma. [22]
The most common side effects include cytokine release syndrome, infections, neutropenia, pyrexia (fever), anemia, thrombocytopenia, and diarrhea. [ 1 ] Odronextamab was approved for medical use in the European Union in August 2024.
Other side effects include redness, swelling, peeling or tenderness on the hands or feet (hand foot syndrome), constipation, stomach pain, nausea and muscle pain. [7] Erdafitinib may cause serious eye problems, including inflamed eyes, inflamed cornea (front part of the eye) and disorders of the retina, an internal part of the eye. [7]
Datopotamab deruxtecan, sold under the brand name Datroway, is an anti-cancer medication used for the treatment of breast cancer. [1] [2] It is a Trop-2-directed antibody and topoisomerase inhibitor antibody-drug conjugate.
This side effect was most common in guys who took 10 to 20 milligrams of Cialis a day. Tadalafil Side Effects Long-Term There are no known long-term side effects of tadalafil.
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