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Image of CD4 co-receptor binding to MHC (Major Histocompatibility Complex) non-polymorphic region. In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as helper T cells, monocytes, macrophages, and dendritic cells.
CDemu is a free and open-source virtual drive software, designed to emulate an optical drive and optical disc (including CD-ROMs and DVD-ROMs) on the Linux operating system.. As of 30 June 2019, CDemu is not available in the official repositories of Debian, Ubuntu and Fedora Linux for any release, but it is available via official PPA for Ubuntu and COPR for Fedora Linux.
CD4 immunoadhesin was first developed in the mid-1990s as a potential therapeutic agent and treatment for HIV/AIDS. The protein is a fusion of the extracellular domain of the CD4 receptor and the Fc domain of human immunoglobulin G (IgG), the most abundant antibody isotype in the human body. [1]
Boehme et al. demonstrated this interesting dual outcome by blocking the binding of CD4 to MHC-II which prevented the programmed cell death reaction that active T-cells typically display. [6] The CD4 receptor is composed of four concatamerized Ig-like domains and is anchored to the cell membrane by a single transmembrane domain.
Gp120 binds to a CD4 and a co-receptor (CCR5 or CXCR4), found on susceptible cells such as Helper T cells and macrophages. [5] As a result, a cascade of conformational changes occurs in the gp120 and gp41 proteins. These conformational changes start with gp120 that rearranges to expose the binding sites for the coreceptors mentioned above.
Linux Terminal Server Project (LTSP) is a free and open-source terminal server for Linux that allows many people to simultaneously use the same computer. Applications run on the server with a terminal known as a thin client (also known as an X terminal) handling input and output. Generally, terminals are low-powered, lack a hard disk and are ...
In programming and software design, a binding is an application programming interface (API) that provides glue code specifically made to allow a programming language to use a foreign library or operating system service (one that is not native to that language).
For example, pressing Alt+f in Xfce's terminal emulator window does not move the cursor forward one word, but activates "File" in the menu of the terminal window, unless that is disabled in the emulator's settings. Tab ↹ : Autocompletes from the cursor position. Ctrl+a : Moves the cursor to the line start (equivalent to the key Home).