Search results
Results from the WOW.Com Content Network
Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the COX enzyme. [1] This makes aspirin different from other NSAIDs (such as diclofenac and ibuprofen), which are reversible inhibitors; aspirin creates an allosteric change in the structure of the COX enzyme. [2]
The illustration shows how PAD can affect arteries in the legs. Figure A shows a normal artery with normal blood flow. The inset image shows a cross-section of the normal artery. Figure B shows an artery with plaque buildup that is partially blocking blood flow. The inset image shows a cross-section of the narrowed artery.
Aspirin helps prevent blood clots from forming, which is the leading cause of heart attack and stroke, but the drug also carries a risk of bleeding. That risk can outweigh aspirin’s benefits in ...
The process is the opposite of vasodilation, the widening of blood vessels. The process is particularly important in controlling hemorrhage and reducing acute blood loss. When blood vessels constrict, the flow of blood is restricted or decreased, thus retaining body heat or increasing vascular resistance.
A variety of things can affect blood circulation: blood vessel health, blood pressure, thyroid function, hydration, heart health, exercise, and blood viscosity. (More on this in a moment.)
High blood pressure, also known as hypertension, can result from an unhealthy lifestyle or certain health conditions, such as diabetes or obesity. The condition can also occur during pregnancy ...
Because blood flow to the kidney first reaches the renal cortex (outside) and then the renal medulla (inside), the deeper structures of the kidney are most sensitive to decreased blood flow. Thus the innermost structures of the kidney, known as the renal papillae , are especially dependent on prostaglandin synthesis to maintain adequate blood flow.
Compartment syndrome usually presents within a few hours of an inciting event, but may present anytime up to 48 hours after. [9] The limb affected by compartment syndrome is often associated with a firm, wooden feeling or a deep palpation, and is usually described as feeling tight.