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Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the COX enzyme. [1] This makes aspirin different from other NSAIDs (such as diclofenac and ibuprofen), which are reversible inhibitors; aspirin creates an allosteric change in the structure of the COX enzyme. [2]
Aspirin helps prevent blood clots from forming, which is the leading cause of heart attack and stroke, but the drug also carries a risk of bleeding. That risk can outweigh aspirin’s benefits in ...
The illustration shows how PAD can affect arteries in the legs. Figure A shows a normal artery with normal blood flow. The inset image shows a cross-section of the normal artery. Figure B shows an artery with plaque buildup that is partially blocking blood flow. The inset image shows a cross-section of the narrowed artery.
You may have read or heard about various reports that taking daily aspirin—yes, that old-time resident of your grandmother's medicine cabinet—may have benefits for modern health conditions ...
In general, the safety and effectiveness of alternative medicines have not been scientifically proven [1] and remain largely unknown. [2] Beyond adverse effects from the herb itself, "adulteration, inappropriate formulation , or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life ...
It most commonly affects leg veins, such as the femoral vein. Three factors are important in the formation of a blood clot within a deep vein—these are: the rate of blood flow, the thickness of the blood and; qualities of the vessel wall. Classical signs of DVT include swelling, pain and redness of the affected area. [3]
One of the goals of blood clot prevention is to limit venous stasis as this is a significant risk factor for forming blood clots in the deep veins of the legs. [6] Venous stasis can occur during the long periods of not moving. Thrombosis prevention is also recommended during air travel. [7]
In all the talk of blood vessels, heart disease, the side effect risks of medication and men’s health in general, it’s easy for doctors and nurses to forget the embarrassment element of ED ...
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