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Nocturnal leg cramps are involuntary muscle contractions that occur in the calves, soles of the feet, or other muscles in the body during the night or (less commonly) while resting. The duration of nocturnal leg cramps is variable, with cramps lasting anywhere from a few seconds to several minutes.
The FDA is also cautioning consumers about off-label use of quinine to treat leg cramps. [19] [20] Quinine is approved for treatment of malaria, but was also commonly prescribed to treat leg cramps and similar conditions. Because malaria is life-threatening, the risks associated with quinine use are considered acceptable when used to treat that ...
The causes of leg cramps at night can range from nutrient deficiency to tough workouts. Here, experts break down how to prevent and get rid of leg cramps.
Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis and Raynaud's disease. [1] It is also used to treat nighttime leg cramps, and has been investigated for its effect against migraine. It is orally administered.
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