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The time to complete the search increases linearly as the size of the database increases. MPIblast utilizes parallel processing to speed up the search. The ideal speed for any parallel computation is a complexity of O(n/p), with n being the size of the database and p being the number of processors. This would indicate that the job is evenly ...
Hybrid methods, known as semi-global or "glocal" (short for global-local) methods, search for the best possible partial alignment of the two sequences (in other words, a combination of one or both starts and one or both ends is stated to be aligned). This can be especially useful when the downstream part of one sequence overlaps with the ...
Local and global search with profile Hidden Markov models, more sensitive than PSI-BLAST: Both: Karplus K, Krogh A [15] 1999 SSEARCH Smith-Waterman search, slower but more sensitive than FASTA: Both: SWAPHI: First parallelized algorithm employing the emerging Intel Xeon Phis to accelerate Smith-Waterman protein database search: Protein: Liu Y ...
The Find, Find Next, and Find Previous are used to find occurrences in certain sections of a query sequence. Next N is a command the will be able to go to the next indeterminate (N) nucleotide. Find in a File allows a user to search another file for selected sequences. Do BLAST Search command will perform a BLAST search in a separate web browser.
Paralogs can be identified in single genomes through a sequence comparison of all annotated gene models to one another. Such a comparison can be performed on translated amino acid sequences (e.g. BLASTp, tBLASTx) to identify ancient duplications or on DNA nucleotide sequences (e.g. BLASTn, megablast) to identify more recent duplications.
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The first beta version of CodonCode Aligner was released in April 2003, followed by the first full version in June 2003. Major upgrades were released in 2003, 2004 ...
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