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  2. Bromadiolone - Wikipedia

    en.wikipedia.org/wiki/Bromadiolone

    Warning label on a tube of rat poison containing bromadiolone on a dike of the Scheldt river in Steendorp, Belgium. Bromadiolone is a potent anticoagulant rodenticide.It is a second-generation 4-hydroxycoumarin derivative and vitamin K antagonist, often called a "super-warfarin" for its added potency and tendency to accumulate in the liver of the poisoned organism.

  3. Brodifacoum - Wikipedia

    en.wikipedia.org/wiki/Brodifacoum

    Brodifacoum is a 4-hydroxycoumarin anticoagulant, with a similar mode of action to its historical predecessors dicoumarol and warfarin.However, due to very high potency and long duration of action (elimination half-life of 20 – 130 days), it is characterised as a "second-generation" or "superwarfarin" anticoagulant.

  4. 4-Hydroxycoumarins - Wikipedia

    en.wikipedia.org/wiki/4-Hydroxycoumarins

    The primary mechanism of the 4-hydroxycoumarin drugs is the inhibition of vitamin K epoxide reductase. These compounds are not direct antagonists (in the pharmaceutical sense) of vitamin K, but rather act to deplete reduced vitamin K in tissues.

  5. Coumarin derivatives - Wikipedia

    en.wikipedia.org/wiki/Coumarin_derivatives

    bromadiolone [4] difenacoum [5] auraptene; ensaculin; phenprocoumon (Marcoumar) PSB-SB-487; PSB-SB-1202; scopoletin can be isolated from the bark of Shorea pinanga [6] warfarin (Coumadin) Coumarin is transformed into the natural anticoagulant dicoumarol by a number of species of fungi. [7]

  6. Bromethalin - Wikipedia

    en.wikipedia.org/wiki/Bromethalin

    Mechanism of action [ edit ] Bromethalin works by being metabolised to n-desmethyl-bromethalin and uncoupling mitochondrial oxidative phosphorylation , which causes a decrease in adenosine triphosphate (ATP) synthesis.

  7. Mechanism of action - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action

    In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect. [2] A mechanism of action usually includes mention of the specific molecular targets to which the drug binds, such as an enzyme or receptor . [ 3 ]

  8. Mode of action - Wikipedia

    en.wikipedia.org/wiki/Mode_of_action

    A mechanism of action of a chemical could be "binding to DNA" while its broader mode of action would be "transcriptional regulation". [3] However, there is no clear consensus and the term mode of action is also often used, especially in the study of pesticides, to describe molecular mechanisms such as action on specific nuclear receptors or ...

  9. Diphenadione - Wikipedia

    en.wikipedia.org/wiki/Diphenadione

    Diphenadione is a vitamin K antagonist that has anticoagulant effects and is used as a rodenticide against rats, mice, voles, ground squirrels and other rodents. The chemical compound is an anti-coagulant with active half-life longer than warfarin and other synthetic 1,3-indandione anticoagulants.