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Hyperalgesia (/ ˌ h aɪ p ər æ l ˈ dʒ iː z i ə / or /-s i ə /; hyper from Greek ὑπέρ (huper) 'over' + -algesia from Greek ἄλγος (algos) 'pain') is an abnormally increased sensitivity to pain, which may be caused by damage to nociceptors or peripheral nerves and can cause hypersensitivity to stimulus.
Increased touch sensitivity is referred to as "tactile hyperesthesia", and increased sound sensitivity is called "auditory hyperesthesia". In the context of pain, hyperaesthesia can refer to an increase in sensitivity where there is both allodynia and hyperalgesia .
People with fibromyalgia are hypersensitive to intense stimuli such as bright lights, loud noises, perfumes, and cold temperatures; people with the condition also have hyper-excitable nociceptors. [29] When people with fibromyalgia are subjected to intense stimuli, they experience sensory overload in the form of pain.
A 2015 longitudinal study based on army medical records of Swedish men showed a correlation between low resting heart rate and violence and criminality, with the authors theorising that lower sensitivity to stimulation resulted in increased likelihood of risk-taking and sensation-seeking behaviour – effectively a low sensitivity counterpart ...
A 2019 meta-analysis showed that exercising aerobically can reduce autonomic dysfunction and increase heart rate variability. [139] This happens when patients exercise at least twice a week, for 45–60 minutes at about 60%-80% of the maximum heart rate. [139] Aerobic exercise also decreases anxiety and depression and improves the quality of ...
Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by an abnormally large increase in heart rate upon sitting up or standing. [1] POTS is a disorder of the autonomic nervous system that can lead to a variety of symptoms, [10] including lightheadedness, brain fog, blurred vision, weakness, fatigue, headaches, heart palpitations, exercise intolerance, nausea ...
Hypersensitivity (also called hypersensitivity reaction or intolerance) is an abnormal physiological condition in which there is an undesirable and adverse immune response to an antigen. [ 1 ] [ 2 ] It is an abnormality in the immune system that causes immune diseases including allergies and autoimmunity .
Opioid-induced hyperalgesia (OIH) or opioid-induced abnormal pain sensitivity, also called paradoxical hyperalgesia, is an uncommon condition of generalized pain caused by the long-term use of high dosages of opioids [1] such as morphine, [2] oxycodone, [3] and methadone. [4] [5] OIH is not necessarily confined to the original affected site. [6]