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  2. Loperamide - Wikipedia

    en.wikipedia.org/wiki/Loperamide

    Loperamide, sold under the brand name Imodium, among others, [1] is a medication of the opioid receptor agonist class used to decrease the frequency of diarrhea. [5] [4] It is often used for this purpose in irritable bowel syndrome, inflammatory bowel disease, short bowel syndrome, [4] Crohn's disease, and ulcerative colitis. [5]

  3. Antimotility agent - Wikipedia

    en.wikipedia.org/wiki/Antimotility_agent

    By binding to μ-opioid receptors, loperamide inhibits acetylcholine release and decreases excitation of neurons in the myenteric plexus, which leads to a decrease in peristalsis. [4] Decreasing intestinal motility prolongs the transit time of food content through the digestive tract, which allows for more fluid absorption; thereby alleviating ...

  4. Loperamide/simethicone - Wikipedia

    en.wikipedia.org/wiki/Loperamide/simethicone

    It contains loperamide and simethicone. Loperamide is a μ-opioid receptor agonist that works in the intestines. [1] Although it is an opioid, it has no effects on the central nervous system. It reduces diarrhea by slowing the transit time of contents through the intestinal tract thereby allowing more water to be reabsorbed from the intestinal ...

  5. This Is How Long You Need To Work Out To Actually Lower Your ...

    www.aol.com/long-actually-lower-dementia-risk...

    For starters, as you get older, the smallest blood vessels in the brain can stiffen and harden, and exercise can help to counteract that, explains Amit Sachdev, MD, MS, medical director in the ...

  6. Could stopping NAD depletion be key to slowing down aging? - AOL

    www.aol.com/could-stopping-nad-depletion-key...

    A new study explains how mitochondria act as “reservoirs” to store NAD for cells to use, which could help scientists come up with NAD-boosting therapies to combat aging and age-related diseases.

  7. Are older Americans working past retirement age because they ...

    www.aol.com/finance/older-americans-working-past...

    According to the Transamerica Center for Retirement Research, 56% of baby boomers are either already working past age 70, think they will work past age 70 or don't think they will ever retire.

  8. Peripherally selective drug - Wikipedia

    en.wikipedia.org/wiki/Peripherally_selective_drug

    These peripherally selective opioids can be used as antidiarrheals, for instance loperamide (Imodium). [ 2 ] Mechanisms of peripheral selectivity include physicochemical hydrophilicity and large molecular size, which prevent drug permeation through the lipid bilayer cell membranes of the blood–brain barrier, and efflux out of the brain by ...

  9. Elderly man not given ‘time-critical’ medicine during three ...

    www.aol.com/elderly-man-not-given-time-000100217...

    Only eight of 18 doses of Parkinson’s medication were provided to the patient on time.