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The invention and development of microscopy enabled the observation of 3-D cell morphology with both high spatial and temporal resolution. The dynamic processes of this cell morphology which are controlled by a complex system play an important role in varied important biological processes, such as immune and invasive responses. [12] [13]
Progress in defining the morphology of nerve cells has been slow in its development. It took nearly a century after the acceptance of the cell as the basic unit of life before researchers could agree upon the shape of a neuron. It was originally thought to be an independent globular corpuscle suspended along nerve fibers that looped and coiled. [3]
Metaplasia occurs when a cell of a certain type is replaced by another cell type, which may be less differentiated. It is a reversible process thought to be caused by stem cell reprogramming. Stem cells are found in epithelia and embryonic mesenchyme of connective tissue. A prominent example of metaplasia involves the changes associated with ...
Also, understanding the cell cycle in individual diseased cells, like those in a tumor, is also important, since they will often have a very different cycle than healthy cells. Single-cell analysis of characteristics of the cell cycle allow scientists to understand these properties in greater detail.
While a neuron's electrical properties are important when defining a cell type its morphology, types of neurotransmitters released, neurotransmitter receptors expressed at synapses, as well as the neuron's location in the nervous system and its local circuit are equally important.
Furthermore, cell polarity is important during many types of asymmetric cell division to set up functional asymmetries between daughter cells. Many of the key molecular players implicated in cell polarity are well conserved. For example, in metazoan cells, the PAR-3/PAR-6/aPKC complex plays a fundamental role in cell polarity. While the ...
Cytometers are the instruments which count the blood cells in the common blood test.. Cytometry is the measurement of number and characteristics of cells.Variables that can be measured by cytometric methods include cell size, cell count, cell morphology (shape and structure), cell cycle phase, DNA content, and the existence or absence of specific proteins on the cell surface or in the ...
Cell synchronization is a process by which cells in a culture at different stages of the cell cycle are brought to the same phase. Cell synchrony is a vital process in the study of cells progressing through the cell cycle as it allows population-wide data to be collected rather than relying solely on single-cell experiments.