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Luxdegalutamide, also known as ARV-766, is an investigational oral androgen receptor (AR) degrader being developed by Arvinas for the treatment of metastatic castration-resistant prostate cancer (mCRPC).
Craig M. Crews (born June 1, 1964) is an American scientist at Yale University known for his contributions to chemical biology.He is known for his contributions to the field of induced proximity through his work in creating heterobifunctional molecules that "hijack" cellular processes by inducing the interaction of two proteins inside a living cell. [1]
Biotech and pharmaceutical companies in the New York metropolitan area represent a significant and growing economic component of the New York metropolitan area, [1] [2] the most populous combined statistical area in the United States [3] and one of the most populous megacities in the world.
Indeed put together a list of the best jobs for 2025 to help identify the high-demand roles offering the most promise in today's dynamic job market.
WASHINGTON (Reuters) -A small U.S. security firm is hiring nearly 100 U.S. special forces veterans to help run a checkpoint in Gaza during the Israel-Hamas truce, according to a company ...
Three in five candidates reportedly believe to have encountered one, per job platform Greenhouse’s 2024 State of Job Hunting report. On Greenhouse alone about 18 to 22% of job listings are fake.
Mechanism of an E3 ligase-targeting PROTAC. Proteolysis-targeting chimeras (PROTACs) were first reported by Kathleen Sakamoto, Craig Crews, and Raymond Deshaies in 2001. A chimeric molecule consisting of ovalicin (a MetAP-2 small molecule inhibitor) and IκBα phosphopeptide (a recruiter of the SCFβ-TRCP E3 ligase complex) separated by a linker was constructed and shown to induce MetAP-2 ...
Trump's tariff plans are squarely in focus for investors amid another busy week on Wall Street that will include quarterly reports from more than 100 S&P 500 companies and the January jobs report.