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Craig M. Crews (born June 1, 1964) is an American scientist at Yale University known for his contributions to chemical biology.He is known for his contributions to the field of induced proximity through his work in creating heterobifunctional molecules that "hijack" cellular processes by inducing the interaction of two proteins inside a living cell. [1]
Arvinas Inc (NASDAQ: ARVN ) shares have been on a tear ever since the company issued a platform update in late October. The Analyst Guggenheim Securities analyst Michael Schmidt initiated coverage ...
PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.
Raymond Joseph Deshaies (born September 25, 1961) is an American biochemist and cell biologist. He is senior vice president of global research at Amgen and a visiting associate at the California Institute of Technology (Caltech).
Members of our leadership team will be available for the Q&A session, including Dr. Andrew Baum, who recently joined Pfizer as EVP and chief strategy and innovation officer.
Chimeric small molecule therapeutics are a class of drugs designed with multiple active domains to operate outside of the typical protein inhibition model. While most small molecule drugs inhibit target proteins by binding their active site, chimerics form protein-protein ternary structures to induce degradation or, less frequently, other protein modifications.
Postel-Vinay earned her medical degree from the University René Descartes Paris V in 2010. As member of Olivier Delattre's team at the Institut Curie, she contributed to important human genetic work on Ewing's sarcoma, which led to the identification of loci associated with the risk of developing this pediatric tumor (published in the journal Nature Genetics in 2012).
51185 58799 Ensembl ENSG00000113851 ENSMUSG00000005362 UniProt Q96SW2 Q8C7D2 RefSeq (mRNA) NM_001173482 NM_016302 NM_021449 NM_175357 RefSeq (protein) NP_001166953 NP_057386 NP_067424 NP_780566 Location (UCSC) Chr 3: 3.14 – 3.18 Mb Chr 6: 106.76 – 106.78 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cereblon is a protein that in humans is encoded by the CRBN gene. The gene that ...