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S.M., sometimes referred to as SM-046, is an American woman with a peculiar type of brain damage that physiologically reduces her ability to feel fear.First described by scientists in 1994, [1] she has had exclusive and complete bilateral amygdala destruction since late childhood as a consequence of Urbach–Wiethe disease.
Amygdalotomy, also known as amygdalectomy, is a form of psychosurgery which involves the surgical removal or destruction of the amygdala, or parts of the amygdala.It is usually a last-resort treatment for severe aggressive behavioral disorders and similar behaviors including hyperexcitability, violent outbursts, and self-mutilation.
Amygdalohippocampectomy is a surgical procedure for the treatment of epilepsy.It consists of the removal of the hippocampus, which has a role in memory, spatial awareness, and navigation, [1] and the amygdalae, which have a role in the processing and memory of emotional reactions, [2] both structures forming part of the limbic system of the brain.
The amygdala is known to have a role in the "fight-or-flight response", and the hippocampus functions to form memories of the stimulus and the emotions associated with it. [13] The role of the BNST in the acoustic startle reflex may be attributed to specific areas within the nucleus responsible for stress and anxiety responses. [ 12 ]
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Human brain in the coronal orientation. Amygdalae are shown in dark red. The amygdala (/ ə ˈ m ɪ ɡ d ə l ə /; pl.: amygdalae / ə ˈ m ɪ ɡ d ə l i,-l aɪ / or amygdalas; also corpus amygdaloideum; Latin from Greek, ἀμυγδαλή, amygdalē, 'almond', 'tonsil' [1]) is a paired nuclear complex present in the cerebral hemispheres of vertebrates.
The amygdala - the fear response system in our brain thought to be involved in the origin of panic attacks When panic attacks occur, people experience the sudden onset of fear and anxiety in the setting of no actual perceived threat (ex. your mind believes there is something threatening your wellbeing, but there is nothing actual life ...
Complex regional pain syndrome (CRPS type 1 and type 2), sometimes referred to by the hyponyms reflex sympathetic dystrophy (RSD) or reflex neurovascular dystrophy (RND), is a rare and severe form of neuroinflammatory and dysautonomic disorder causing chronic pain, neurovascular, and neuropathic symptoms.