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Microscopic colitis refers to two related medical conditions which cause diarrhea: collagenous colitis and lymphocytic colitis. [ 2 ] [ 3 ] Both conditions are characterized by the presence of chronic non-bloody watery diarrhea , normal appearances on colonoscopy and characteristic histopathology findings of inflammatory cells.
Collagenous colitis, and microscopic colitis as a whole, is sometimes considered to be an inflammatory bowel disease (IBD) along with Crohn's disease and ulcerative colitis. However, little is known about the etiology of microscopic colitis, and so the degree of similarity to the inflammatory bowel diseases is uncertain. [1] [2]
Activation of the endocannabinoid system was found efficient in ameliorating colitis and increasing the survival rate of mice, and reducing remote organ changes induced by colitis, further suggest that modulation of this system is a potential therapeutic approach for IBDs and the associated remote organ lesions.
What causes microscopic colitis and who gets it? It occurs in males and females of all ages, but women are more likely to be affected and it mostly presents later in adulthood.
Over-the-counter antidiarrheal drugs may be effective for some people with lymphocytic colitis. Anti-inflammatory drugs, such as salicylates, mesalazine, and systemic corticosteroids may be prescribed for people who do not respond to other drug treatment. The long-term prognosis for this disease is good with a proportion of people suffering ...
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Crohn's & Colitis UK (formerly NACC) is a UK charity dedicated to Crohn's disease, ulcerative colitis, and other forms of inflammatory bowel disease (IBD). It was founded in 1979 as the National Association for Colitis and Crohn's Disease .
One study found that the medication tulisokibart may help people with moderate to severe ulcerative colitis achieve clinical remission. Ulcerative colitis is a chronic condition characterized by ...