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People with inflammatory bowel disease account for less than 2% of colon cancer cases yearly. [34] In those with Crohn's disease, 2% get colorectal cancer after 10 years, 8% after 20 years, and 18% after 30 years. [34] In people who have ulcerative colitis, approximately 16% develop either a cancer precursor or cancer of the colon over 30 years ...
Most children develop signs and symptoms shortly after birth. However, others may be diagnosed later in infancy or early childhood. [4] [5] About half of all children with Hirschsprung's disease are diagnosed in the first year of life. [4] Complications may include enterocolitis, megacolon, bowel obstruction and intestinal perforation. [1] [2]
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types. [3] Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas UC primarily affects the colon ...
About 20 to 25% of patients presenting with inflammatory bowel disease are children under 18 years old, while 80% are adolescents. Additionally, the incidence of Crohn's disease in children is on the rise, with 2.5–11.4 new cases per 100,000 and a prevalence of 58 per 100,000. [44]
Bowel cancer is the fourth most common type of cancer in the UK
From early adolescence, patients with this condition gradually (and much of the time asymptomatically) develop hundreds to thousands of colorectal polyps (and sometimes polyps elsewhere)—small abnormalities at the surface of the intestinal tract, especially in the large intestine including the colon or rectum.
The condition is relatively rare, affecting approximately 1 in 100,000 people per year. It affects mainly adults aged 30–50. Females are affected slightly more often than males. The disorder can be confused clinically with rectal cancer or other conditions such as inflammatory bowel disease, even when a biopsy is done. [2]
The extracolonic tumors may include osteomas of the skull, thyroid cancer, epidermoid cysts, fibromas, [4] as well as the occurrence of desmoid tumors in approximately 15% of affected individuals. Desmoid tumors are fibrous tumors that usually occur in the tissue covering the intestines and may be provoked by surgery to remove the colon.
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