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Since 2009, two tyrosine kinase inhibitors - masitinib (trade name Masivet) and toceranib (trade name Palladia) - have been approved for the treatment of mastocytomas in dogs in the EU. [17] [37] [38] Masitinib is approved for the treatment of unresectable grade 2 and 3 (or high-grade) mastocytomas with c-KIT mutation.
The English bulldog, a typically brachycephalic dog breed, may have brachycephalic syndrome. A Peke-face Exotic shorthair.. Brachycephalic obstructive airway syndrome (BOAS), also known as brachycephalic airway obstructive syndrome (BAOS), brachycephalic airway syndrome (BAS), and brachycephalic syndrome (BS), [1] is a pathological condition affecting short nosed dogs and cats which can lead ...
Mast cell tumors are known among veterinary oncologists as 'the great pretenders' because their appearance can be varied, from a wart-like nodule to a soft subcutaneous lump (similar on palpation to a benign lipoma) to an ulcerated skin mass. Most mast cell tumors are small, raised lumps on the skin. They may be hairless, ulcerated, or itchy.
Osteoarthritis*, also known as degenerative arthritis, is a common condition in dogs characterized by progressive deterioration of articular cartilage in the joints of the limbs. It can cause a great deal of pain and lameness. Treatment options include medications such as NSAIDs, corticosteroids, and joint fluid modifiers such as ...
Often, successful treatment of and recovery from laryngeal cancer will involve expertise outside of the realms of surgery or oncology. Physical therapists , occupational therapists , speech therapists , psychiatrists , psychologists , oral/maxillofacial surgeons , dentists , neurologists , neurosurgeons , and endocrinologists may all become ...
Reinke's edema is commonly diagnosed in middle-aged females with a history of smoking (aged 50 years or older). Because males have lower pitched voices than females, males are less likely to observe significant changes in the voice and are therefore less likely to seek treatment. Females also report more physical discomfort due to Reinke's edema.
A common symptom of laryngeal papillomatosis is a change in voice quality. More specifically, hoarseness is observed. [4] [5] As a consequence of the narrowing of the laryngeal or tracheal parts of the airway, shortness of breath, chronic cough and stridor (i.e. noisy breathing which can sound like a whistle or a snore), can be present.
Investigations into idiopathic laryngeal paralysis by two groups (in Michigan and Tennessee) between 2005 and 2013 showed that dogs with ILP did not only suffer dysfunction of the laryngeal nerves; they found that this was just one prominent symptom of what was a very gradually progressing polyneuropathy of old age, which also affected other ...