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It is a rare blood condition in which the β-pyrrole ring of the hemoglobin molecule has the ability to bind irreversibly to any substance containing a sulfur atom. [ 1 ] [ 2 ] When hydrogen sulfide (H 2 S) (or sulfide ions ) and ferrous ions combine in the heme of hemoglobin, the blood is thus incapable of transporting oxygen to the tissues.
Over half of groundwater sources in India have fluoride above recommended levels. [9] Fluorosis can also occur as a result of volcanic activity. The 1783 eruption of the Laki volcano in Iceland is estimated to have killed about 22% of the Icelandic population, and 60% of livestock, as a result of fluorosis and sulfur dioxide gases. [10]
Mineral deficiency is a lack of the dietary minerals, the micronutrients that are needed for an organism's proper health. [1] The cause may be a poor diet, impaired uptake of the minerals that are consumed, or a dysfunction in the organism's use of the mineral after it is absorbed.
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Most individuals with G6PD deficiency are asymptomatic.When it induces hemolysis, it is usually is short-lived. [5]Most people who develop symptoms are male, due to the X-linked pattern of inheritance, but female carriers can be affected due to unfavorable lyonization or skewed X-inactivation, where random inactivation of an X-chromosome in certain cells creates a population of G6PD-deficient ...
Phenol sulfur transferase deficiency, in short PST deficiency, is the lack or the reduced activity of the functional enzyme phenol sulfur transferase, which is crucial in the detoxification of mainly phenolic compounds by catalysing the sulfate conjugation of the hydroxyl groups in the toxic phenolic compounds to result in more hydrophilic forms for more efficient excretion.
Yokkaichi asthma (四日市ぜんそく, Yokkaichi zensoku) refers to cases of chronic obstructive pulmonary disease, chronic bronchitis, pulmonary emphysema, and bronchial asthma in humans and various environmental changes usually attributed to sulfur dioxide (SO 2) emissions which appeared as smog over the city of Yokkaichi in Mie Prefecture, Japan between 1960 and 1972, though other SO x ...
Often it begins in people aged 15 to 30 years, or among those over 60. [1] Males and females appear to be affected in equal proportions. [7] It has also become more common since the 1950s. [7] [9] Together, ulcerative colitis and Crohn's disease affect about a million people in the United States. [176]