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It is a more potent derivative of triamcinolone, and is about eight times as potent as prednisone. [14] Most forms of triamcinolone acetonide are prescription drugs. In 2014, the U.S. Food and Drug Administration (FDA) made triamcinolone acetonide an over-the-counter drug in the United States in nasal spray form under the brand name Nasacort. [14]
Serious side effects may include psychosis, increased risk of infections, adrenal suppression, and bronchospasm. [6] Use in pregnancy is generally safe. [7] It works by decreasing inflammation and immune system activity. [6] Triamcinolone was patented in 1956 and came into medical use in 1958. [8] It is available as a generic medication. [9]
Side effects. Topical decongestants should not be used for longer than a week as prolonged use may result in rhinitis medicamentosa (rebound nasal congestion). [13] Common side effects for oral decongestants include insomnia, hypertension (elevated blood pressure), and difficulty in urination. [12]
Flunisolide nasal spray is absorbed into the circulatory system (blood). [3] Corticosteroid nasal sprays may affect the hypothalamic-pituitary-adrenal axis function in humans. [7] After obtaining the desired clinical effect, the maintenance dose should be reduced to the smallest amount required to control the symptoms. The amount can be as low ...
Decongestant nasal sprays are advised for short-term use only, preferably 5 to 7 days at maximum. Some doctors advise to use them 3 days at maximum. A recent clinical trial has shown that a corticosteroid nasal spray may be useful in reversing this condition. [3] Topical nasal decongestants include: Oxymetazoline; Phenylephrine; Xylometazoline
According to Forbes, there have been 45,000 reported cases of side effects related to fluoroquinolones. 23.1 million patients filled prescriptions for oral flouroquinolones in 2011.
Rhinitis medicamentosa (or RM, also known as rebound congestion) is a condition of rebound nasal congestion suspected to be brought on by extended use of topical decongestants (e.g., oxymetazoline, phenylephrine, xylometazoline, and naphazoline nasal sprays) and certain oral medications (e.g., sympathomimetic amines and various 2-imidazolines) that constrict blood vessels in the lining of the ...
Systemic steroids such as prednisone tablets and intramuscular triamcinolone acetonide or glucocorticoid (such as betamethasone) injection are effective at reducing nasal inflammation, [citation needed] but their use is limited by their short duration of effect and the side-effects of prolonged steroid therapy. [55]
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