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Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a form of hormone therapy in which androgens, often testosterone, are supplemented or replaced. It typically involves the administration of testosterone through injections, skin creams, patches, gels, pills, or subcutaneous pellets.
In men with verifiably deficient levels—generally below 300 ng/dL—and low-T symptoms (fatigue, decreased sex drive), replacement can ratchet up desire, sexual activity, physical function, and ...
As of 2016, the International Society for the Study of the Aging Male defines late-onset hypogonadism as a series of symptoms in older adults related to testosterone deficiency that combines features of both primary and secondary hypogonadism; the European Male Aging Study (a prospective study of ~3000 men) [10] defined the condition by the presence of at least three sexual symptoms (e.g ...
However, a 2014 review showed no benefit on the mood of the men with normal levels of testosterone or on the mood of the older men with low testosterone. [148] Conversely, a 2009 review found that testosterone had an antidepressant effect in men with depression, especially those with hypogonadism, HIV/AIDS, and in the elderly. [149]
Male primary or hypergonadotropic hypogonadism is often treated with testosterone replacement therapy if they are not trying to conceive. [13] In short- and medium-term testosterone replacement therapy the risk of cardiovascular events (including strokes and heart attacks and other heart diseases) is not increased. The long-term safety of the ...
When men start testosterone therapy, it is typically given in a gel with a dose of 50-100 mg a day. Women, on the other hand, are recommended to take just 5 mg a day — 10% of the dose of a man.
They typically factor in your labs and your symptoms before prescribing testosterone replacement therapy. “The goal is general well-being,” says Ahmed El-Zawahry, M.D. , a urologist at the ...
[11] [4] Testosterone cypionate is converted by the body to testosterone that has both androgenic effects and anabolic effects, which make it useful for producing masculinization and suitable for androgen replacement therapy; [4] still, the relative potency of these effects can depend on various factors and is a topic of ongoing research.
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