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Squared deviations from the mean (SDM) result from squaring deviations.In probability theory and statistics, the definition of variance is either the expected value of the SDM (when considering a theoretical distribution) or its average value (for actual experimental data).
In bioinformatics, the root mean square deviation of atomic positions is the measure of the average distance between the atoms of superimposed proteins. In structure based drug design , the RMSD is a measure of the difference between a crystal conformation of the ligand conformation and a docking prediction.
The standard deviation (SD) is obtained as the square root of the variance. Variance is a measure of dispersion , meaning it is a measure of how far a set of numbers is spread out from their average value.
Mean Signed Deviation is a statistical measure used to assess the average deviation of a set of values from a central point, usually the mean. It is calculated by taking the arithmetic mean of the signed differences between each data point and the mean of the dataset.
A little algebra shows that the distance between P and M (which is the same as the orthogonal distance between P and the line L) (¯) is equal to the standard deviation of the vector (x 1, x 2, x 3), multiplied by the square root of the number of dimensions of the vector (3 in this case).
The MSE either assesses the quality of a predictor (i.e., a function mapping arbitrary inputs to a sample of values of some random variable), or of an estimator (i.e., a mathematical function mapping a sample of data to an estimate of a parameter of the population from which the data is sampled).
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