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Type I xanthinuria can be caused by a deficiency of xanthine oxidase, which is an enzyme necessary for converting xanthine to uric acid. [2] Type II xanthinuria and molybdenum cofactor deficiency lack one or two other enzyme activities in addition to xanthine oxidase.
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [5] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
Xanthinuria is a rare genetic disorder where the lack of xanthine oxidase leads to high concentration of xanthine in blood and can cause health problems such as renal failure. There is no specific treatment, affected people are advised by doctors to avoid foods high in purine and to maintain a high fluid intake.
Scanning electron micrograph of the surface of a kidney stone showing tetragonal crystals of weddellite (calcium oxalate dihydrate) emerging from the amorphous central part of the stone (the horizontal length of the picture represents 0.5 mm of the figured original) Multiple kidney stones composed of uric acid and a small amount of calcium ...
Haig argued that excess uric acid was a major cause of disease. For example, he attributed anemia, Bright's disease, cancer, diabetes, heart disease, pneumonia and rheumatism to excess uric acid. [3] Haig stated that the uric-acid free diet greatly improved his health and he had eighteen years of experience on the diet. [3]
Generally, however, these guidelines agree that highly processed foods contain high amounts of total and added sugars, fats, and/or salt, low amounts of dietary fiber, use industrial ingredients ...
In fact, it has been found that some vegetables may yield greater benefits than others, while other veggies are actually really bad for us. For example, one vegetable has the same sugary response ...
Haig's uric-acid free diet (known as Haig's diet) required the elimination of every food containing high amounts of purines that could be metabolized into uric acid. [16] On this diet all meats, legumes and some vegetables were eliminated including asparagus, beans, lentils, mushrooms, peas and whole grain products. [16]
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