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Multiple sclerosis (MS) is an autoimmune disorder in which the immune system attacks and destroys the myelin sheath of nerve cells. It most commonly strikes people between the ages of 20 and 40.
Treatment in MS Phase III studies is usually two years per patient. In July 2021, the FDA gave the go-ahead for an investigational new drug application (IND) for the phase 3 ENSURE program, which will evaluate IMU-838 in patients with relapsing-remitting multiple sclerosis (RRMS).
Research in multiple sclerosis may find new pathways to interact with the disease, improve function, curtail attacks, or limit the progression of the underlying disease. . Many treatments already in clinical trials involve drugs that are used in other diseases or medications that have not been designed specifically for multiple sclero
multiple sclerosis, chronic lymphocytic leukemia Ulocuplumab [55] mab: human: CXCR4 (CD184) hematologic malignancies Urelumab [16] mab: human: 4-1BB (CD137) cancer etc. Urtoxazumab [9] mab: humanized: Escherichia coli: diarrhoea caused by E. coli: Ustekinumab [49] Stelara: mab: human: IL-12, IL-23: Y: multiple sclerosis, psoriasis, psoriatic ...
Here's a quick primer on multiple sclerosis. MS is an autoimmune disease that attacks myelin—the fatty insulation that surrounds the nerves in the spinal cord and brain. In severe cases, MS can ...
"Regardless of the substance administered (leflunomide or teriflunomide), it is the same molecule (teriflunomide)—the one exerting the pharmacological, immunological or metabolic action in view of restoring, correcting or modifying physiological functions, and does not present, in clinical use, a new chemical entity to patients."
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