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Fibroblast growth factor 1 (FGF-1) also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1 gene. [ 5 ] [ 6 ] It is synthesized as a 155 amino acid polypeptide, whose mature form is a non- glycosylated 17-18 kDa protein.
Members FGF1 through FGF10 all bind fibroblast growth factor receptors (FGFRs). FGF1 is also known as acidic fibroblast growth factor, and FGF2 is also known as basic fibroblast growth factor. Members FGF11, FGF12, FGF13, and FGF14, also known as FGF homologous factors 1-4 (FHF1-FHF4), have been shown to have distinct functions compared to the ...
Fibroblast growth factor receptor 1 on the Atlas of Genetics and Oncology; FGFR1 human gene location in the UCSC Genome Browser. FGFR1 human gene details in the UCSC Genome Browser. Overview of all the structural information available in the PDB for UniProt: P11362 (Human Fibroblast growth factor receptor 1) at the PDBe-KB.
The natural alternate splicing of four fibroblast growth factor receptor (FGFR) genes results in the production of over 48 different isoforms of FGFR. [3] These isoforms vary in their ligand-binding properties and kinase domains, however all share the common extracellular region composed of three immunoglobulin (Ig)-like domains (D1-D3), and ...
58249 Ensembl ENSG00000172500 ENSMUSG00000024911 UniProt O43427 Q9JI19 RefSeq (mRNA) NM_004214 NM_198897 NM_001253832 NM_021438 RefSeq (protein) NP_004205 NP_942600 NP_001240761 NP_067413 Location (UCSC) Chr 11: 65.88 – 65.89 Mb Chr 19: 5.51 – 5.52 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Acidic fibroblast growth factor intracellular-binding protein is a protein that in ...
One of the worst calamities to touch the village occurred in 1916, when a disastrous fire destroyed a large part of the business area and several homes. As a result of this tragedy, a water tower was erected on Main Street near the present day Sheriff's Annex, where it stood until Hurricane Betsy destroyed it in 1965. By 1948 Lockport's ...
9982 14181 Ensembl ENSG00000137440 ENSMUSG00000048373 UniProt Q14512 O70514 RefSeq (mRNA) NM_005130 NM_001271616 NM_008009 RefSeq (protein) NP_005121 NP_001258545 NP_032035 Location (UCSC) Chr 4: 15.94 – 15.94 Mb Chr 5: 44.14 – 44.14 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Fibroblast growth factor-binding protein 1 is a protein that in humans is encoded by the FGFBP1 gene ...
Fibroblast growth factor receptor-like 1 is a protein that in humans is encoded by the FGFRL1 gene. [ 5 ] The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution.