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Iron dextran preparation [31] Routes Dosage forms Strengths Brand names Manufacturer Parenteral: Injection, for IV use: equivalent to 50 mg of elemental iron per mL: Dexferrum® American Regent Injection, for IV or IM use: equivalent to 50 mg of elemental iron per mL: INFeD® Watson
high molecular weight iron dextran 165 000 low molecular weight iron dextran 289 000 - 444 000 34 000 - 60 000 750 000 150 000 150 000 Maximum approved dosage (mg) 100 100 125 200 510 20 mg per kg 1000 mg if patient weight is > 66 kg Test dose required Yes Yes No No No No No Iron concentration (mg/mL) 50 50 12.5 20 30 100 50
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
ATC code B03 Antianemic preparations is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Iron isomaltoside 1000 (brand name Monofer) is a formulation of parenteral iron that has a matrix structure that results in very low levels of free iron and labile iron. It can be given at high doses – 20 mg/kg in a single visit – no upper dose limit.
Dextran 70 is a type of fluid given by injection into a vein to expand blood volume. [1] Specifically it is used for shock such as that caused by bleeding or burns when blood transfusions are not quickly available. [2] However, it does not carry oxygen. [2] Common side effects include vomiting, fever, and joint pains. [2]
Microspheres composed of dextran have several advantages as a drug delivery system including controlled drug release, localized drug concentration, and reduced adverse reactions. Controlled drug release by these dextran microparticles is achieved by degradation, which is the breakdown of chemical bonds in the molecular structure of the ...
Iron sucrose is a dark brown liquid solution. It is administered intravenously and is only used when a patient with iron deficiency cannot be treated using oral iron options. [5] It is a generally effective drug, with more than 80% of patients responding to treatment. Iron sucrose has ~20 mg of iron per mL of solution.