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  2. Ramipril - Wikipedia

    en.wikipedia.org/wiki/Ramipril

    Ramipril, sold under the brand name Altace among others, is an ACE inhibitor type medication used to treat high blood pressure, heart failure, ...

  3. ACE inhibitor - Wikipedia

    en.wikipedia.org/wiki/ACE_inhibitor

    Some believe ramipril's additional benefits may be shared by some or all drugs in the ACE-inhibitor class. However, ramipril currently remains the only ACE inhibitor for which such effects are actually evidence-based. [64] A meta-analysis confirmed that ACE inhibitors are effective and certainly the first-line choice in hypertension treatment.

  4. Discovery and development of ACE inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The development of the nonapeptide teprotide (Glu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro), which was originally isolated from the venom of the Brazilian pit viper Bothrops jararaca, greatly clarified the importance of ACE in hypertension.

  5. ACE inhibitor and thiazide combination - Wikipedia

    en.wikipedia.org/wiki/ACE_inhibitor_and_thiazide...

    An ACE inhibitor and thiazide combination is a drug combination used to treat hypertension (high blood pressure). They are given by mouth.ACE inhibitors reduce the activity of angiotensin-converting enzyme (ACE) which produces angiotensin II, a hormone that constricts blood vessels.

  6. Rilmenidine - Wikipedia

    en.wikipedia.org/wiki/Rilmenidine

    Rilmenidine, an oxazoline compound with antihypertensive properties, acts on both medullary and peripheral vasomotor structures.. Rilmenidine is a imidazoline analog and shows greater selectivity for imidazoline receptors than for cerebral alpha2-adrenergic receptors, distinguishing it from reference alpha2-agonists, and conferring additional anti-inflammatory actions not shared with most ...

  7. Enalapril - Wikipedia

    en.wikipedia.org/wiki/Enalapril

    Enalapril, sold under the brand name Vasotec among others, is an ACE inhibitor medication used to treat high blood pressure, diabetic kidney disease, and heart failure. [5] ...

  8. Quinapril - Wikipedia

    en.wikipedia.org/wiki/Quinapril

    In April of 2022, Pfizer voluntarily recalled five batches of the drug because of the presence of a nitrosamine, N-Nitroso-quinapril.Testing found that the amount of nitrosamines was above the acceptable daily intake level (all humans are exposed to nitrosamines up to a certain daily level by cured and grilled meats, water, dairy products, and vegetables) set by the U.S.'s Food and Drug ...

  9. Combination drug - Wikipedia

    en.wikipedia.org/wiki/Combination_drug

    A combination drug or a fixed-dose combination (FDC) is a medicine that includes two or more active ingredients combined in a single dosage form. [1] Terms like "combination drug" or "combination drug product" can be common shorthand for an FDC product (since most combination drug products are currently FDCs), although the latter is more precise if in fact referring to a mass-produced product ...

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