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  2. Energy charge - Wikipedia

    en.wikipedia.org/wiki/Energy_charge

    Daniel Atkinson showed that when the energy charge increases from 0.6 to 1.0, the citrate lyase and phosphoribosyl pyrophosphate synthetase, two enzymes controlling anabolic (ATP-demanding) pathways are activated, [2] [3] while the phosphofructokinase and the pyruvate dehydrogenase, two enzymes controlling amphibolic pathways (supplying ATP as ...

  3. Merck Manual of Diagnosis and Therapy - Wikipedia

    en.wikipedia.org/wiki/Merck_Manual_of_Diagnosis...

    The first edition of The Merck Manual was published in 1899 by Merck & Co., Inc. for physicians and pharmacists and was titled Merck's Manual of the Materia Medica. [6] [7] The 192 page book which sold for US $1.00, was divided into three sections, Part I ("Materia Medica") was an alphabetical listing of all known compounds thought to be of therapeutic value with uses and doses; Part II ...

  4. PDFtk - Wikipedia

    en.wikipedia.org/wiki/Pdftk

    PDFtk (short for PDF Toolkit) is a toolkit for manipulating Portable Document Format (PDF) documents. [ 3 ] [ 4 ] It runs on Linux , Windows and macOS . [ 5 ] It comes in three versions: PDFtk Server ( open-source command-line tool ), PDFtk Free ( freeware ) and PDFtk Pro ( proprietary paid ). [ 2 ]

  5. Kidney stone disease - Wikipedia

    en.wikipedia.org/wiki/Kidney_stone_disease

    Stones less than 5 mm (0.2 in) in diameter pass spontaneously in up to 98% of cases, while those measuring 5 to 10 mm (0.2 to 0.4 in) in diameter pass spontaneously in less than 53% of cases. [ 85 ] Stones that are large enough to fill out the renal calyces are called staghorn stones and are composed of struvite in a vast majority of cases ...

  6. ATP hydrolysis - Wikipedia

    en.wikipedia.org/wiki/ATP_hydrolysis

    Structure of ATP Structure of ADP Four possible resonance structures for inorganic phosphate. ATP hydrolysis is the catabolic reaction process by which chemical energy that has been stored in the high-energy phosphoanhydride bonds in adenosine triphosphate (ATP) is released after splitting these bonds, for example in muscles, by producing work in the form of mechanical energy.

  7. Mitochondrion - Wikipedia

    en.wikipedia.org/wiki/Mitochondrion

    [68] [69] [70] ATP levels differ at various stages of the cell cycle suggesting that there is a relationship between the abundance of ATP and the cell's ability to enter a new cell cycle. [71] ATP's role in the basic functions of the cell make the cell cycle sensitive to changes in the availability of mitochondrial derived ATP. [ 71 ]

  8. Hypoxia-inducible factor - Wikipedia

    en.wikipedia.org/wiki/Hypoxia-inducible_factor

    These include glycolysis enzymes, which allow ATP synthesis in an oxygen-independent manner, and vascular endothelial growth factor (VEGF), which promotes angiogenesis. HIF-1 acts by binding to hypoxia-responsive elements (HREs) in promoters that contain the sequence 5'-RCGTG-3' (where R is a purine, either A or G).

  9. History of PDF - Wikipedia

    en.wikipedia.org/wiki/History_of_PDF

    PDF/VT (since 2010 - ISO 16612-2) - a.k.a. "PDF for exchange of variable data and transactional (VT) printing" - Graphic technology - Variable data exchange (working in ISO Technical committee 130), based on PDF 1.6 as restricted by PDF/X-4 and PDF/X-5 [52] PDF/UA (since 2012 - ISO 14289-1) - a.k.a. "PDF for Universal Accessibility" - Document ...

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