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Minoxidil sulfate is a sulfate ester of minoxidil, not a sulfate salt of the compound. [3] However, minoxidil sulfate forms an inner salt , which makes it more hydrophobic than minoxidil. [ 3 ] This is in contrast to most sulfate esters, which are usually more hydrophilic than their non-ester forms. [ 3 ]
Minoxidil is a medication used for the treatment of high blood pressure and pattern hair loss. [ 5 ] [ 6 ] [ 7 ] It is an antihypertensive and a vasodilator . [ 10 ] It is available as a generic medication by prescription in oral tablet form and over the counter as a topical liquid or foam.
Minoxidil is one of the most widely used, FDA-approved hair loss treatments on the market. It’s used by millions of people all around the world to help fight against hair loss and stimulate new ...
A 2023 study comparing the efficacy and safety of 1-milligram daily oral minoxidil and 5% topical minoxidil found that topical minoxidil had a better therapeutic effect (meaning it worked a little ...
As minoxidil sulfate, minoxidil shortens your hair’s telogen phase — the resting phase of the hair growth cycle — and moves your hair follicles into an active growth state, referred to as ...
The SULT1A1 enzyme is expressed in outer roots sheath of hair follicles. Minoxidil, the only US FDA approved topical drug for re-growing hair in male and female pattern hair loss (androgenetic alopecia patients) is a pro-drug. Minoxidil is converted to its active form (minoxidil sulfate) by the hair sulfotransferase enzyme (SULT1A1). [6]
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