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  2. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    In combination with palbociclib and fulvestrant for the treatment of adults with endocrine-resistant, PIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth-factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer, as detected by an FDA-approved test, following recurrence on or after completing adjuvant ...

  3. Approved Drug Products with Therapeutic Equivalence ...

    en.wikipedia.org/wiki/Approved_Drug_Products...

    inducing pioneering research and development of new drugs and; enabling competitors to bring low-cost, generic copies of those drugs to market'". [1] The Orange Book identifies drug products approved on the basis of safety and effectiveness by the Food and Drug Administration (FDA) under the Federal Food, Drug, and Cosmetic Act.

  4. Multiple sclerosis drug pipeline - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis_drug...

    Approved in March 2019 for CIS, RRMS and SPMS [11] [12] Ozanimod: oral. It was approved by the FDA in March 2020 with the trade name Zeposia [13] [14] [15] Ponesimod (Ponvory) Five monoclonal antibodies: Alemtuzumab (Lemtrada, Campath). [16] Natalizumab (Tysabri) Ocrelizumab (Ocrevus) [17] which is also approved for primary progressive (PPMS)

  5. List of gene therapies - Wikipedia

    en.wikipedia.org/wiki/List_of_gene_therapies

    Alipogene tiparvovec (Glybera): AAV-based treatment for lipoprotein lipase deficiency (no longer commercially available); Axicabtagene ciloleucel (Yescarta): treatment for large B-cell lymphoma [1]

  6. Sphingosine-1-phosphate receptor modulator - Wikipedia

    en.wikipedia.org/wiki/Sphingosine-1-phosphate...

    Even though it has the drawback of not being a selective receptor modulator it has passed all clinical drug trials and was approved for the market in USA in 2010. [ 3 ] [ 6 ] In the beginning the focus of developing a drug from myriocin was to find an immunosuppressant drug that could be used to prevent rejection of organs during and after a ...

  7. List of Schedule III controlled substances (U.S.) - Wikipedia

    en.wikipedia.org/wiki/List_of_Schedule_III...

    The drug or other substance has a potential for abuse less than the drugs or other substances in schedules I and II. The drug or other substance has a currently [1] accepted medical use in treatment in the United States. Abuse of the drug or other substance may lead to moderate or low physical dependence or high psychological dependence.

  8. Pexidartinib - Wikipedia

    en.wikipedia.org/wiki/Pexidartinib

    In August 2019, it was approved by U.S. FDA for treatment of giant-cell tumor of the tendon sheath (GC-TS). [2] [6] [7] Pexidartinib is available in the US only through the Turalio Risk Evaluation and Mitigation Strategy (REMS) Program. [2] The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. [8]

  9. List of androgens/anabolic steroids available in the United ...

    en.wikipedia.org/wiki/List_of_androgens/anabolic...

    This is a complete list of androgens/anabolic steroids (AAS) and formulations that are approved by the FDA Tooltip Food and Drug Administration and available in the United States. AAS like testosterone are used in androgen replacement therapy (ART), a form of hormone replacement therapy (HRT), and for other indications.