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Choriocarcinoma is a malignant, trophoblastic [1] cancer, usually of the placenta. It is characterized by early hematogenous spread to the lungs. It belongs to the malignant end of the spectrum in gestational trophoblastic disease (GTD). It is also classified as a germ cell tumor and may arise in the testis or ovary.
Bone metastasis, or osseous metastatic disease, is a category of cancer metastases that result from primary tumor invasions into bones. Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing sarcoma are rare; the most common bone tumor is a metastasis. [1] Bone metastases can be classified as osteolytic, osteoblastic ...
In the event the gestational choriocarcinoma has already spread to other parts of the body, bleeding events in other organs may be the first symptom. [3] If the choriocarcinoma has metastasized to the lungs, one of the most common organs of metastasis, then symptoms may include abnormally quick breathing, coughing, and chest pain. [7]
Although intratumoral hemorrhage can occur in any primary or metastatic brain tumor, certain tumors have a greater tendency to bleed, including metastasis from melanoma, choriocarcinoma, and thyroid cancer and the primary brain tumors glioblastoma and oligodendroglioma. [5] 2. Spinal Cord Tumor Presentations
1956 – Metastatic choriocarcinoma cancer is cured with the antifolate, methotrexate [4] 1956 – First bone marrow transplantation performed by E. Donnall Thomas in order to treat leukemia in one of two identical twins, the healthy twin being the donor [17]
A bone tumor is an abnormal growth of tissue in bone, traditionally classified as noncancerous (benign) or cancerous (malignant). [1] [4] Cancerous bone tumors usually originate from a cancer in another part of the body such as from lung, breast, thyroid, kidney and prostate. [1] There may be a lump, pain, or neurological signs from pressure. [1]
M describes distant metastasis (spread of cancer from one part of the body to another). The TNM staging system for all solid tumors was devised by Pierre Denoix of the Institut Gustave Roussy between 1943 and 1952, using the size and extension of the primary tumor, its lymphatic involvement, and the presence of metastases to classify the ...
Cancer is a group of diseases that involve abnormal increases in the number of cells, with the potential to invade or spread to other parts of the body. [1] Not all tumors or lumps are cancerous; benign tumors are not classified as being cancer because they do not spread to other parts of the body. [ 1 ]
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