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Cloning is commonly used to amplify DNA fragments containing whole genes, but it can also be used to amplify any DNA sequence such as promoters, non-coding sequences and randomly fragmented DNA. It is used in a wide array of biological experiments and practical applications ranging from genetic fingerprinting to large scale protein production.
Commercial animal cloning is the cloning of animals for commercial purposes, including animal husbandry, medical research, competition camels and horses, pet cloning, and restoring populations of endangered and extinct animals. [1] The practice was first demonstrated in 1996 with Dolly the sheep.
Molecular cloning takes advantage of the fact that the chemical structure of DNA is fundamentally the same in all living organisms. Therefore, if any segment of DNA from any organism is inserted into a DNA segment containing the molecular sequences required for DNA replication, and the resulting recombinant DNA is introduced into the organism from which the replication sequences were obtained ...
In January 2019, scientists in China reported the creation of five identical cloned gene-edited monkeys, using the same cloning technique that was used with Zhong Zhong and Hua Hua – the first ever cloned monkeys – and Dolly the sheep, and the same gene-editing Crispr-Cas9 technique allegedly used by He Jiankui in creating the first-ever ...
Cloning animals requires procedures that can cause pain and distress, and there can be high failure and mortality rates.” Being able to produce genetically identical monkeys could be useful ...
This technique is currently the basis for cloning animals (such as the famous Dolly the sheep), [30] and has been proposed as a possible way to clone humans. Using SCNT in reproductive cloning has proven difficult with limited success. High fetal and neonatal death make the process very inefficient.
Scientific American concluded in 2016 that the main legacy of Dolly has not been cloning of animals but in advances into stem cell research. [42] Gene targeting was added in 2000, when researchers cloned female lamb Diana from sheep DNA altered to contain the human gene for alpha 1-antitrypsin.
In 2022, Russian researchers found a young bison from over 8,000 years ago in Siberia. Now, they want to clone it.
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