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Pulmonary fibrosis is not currently curable; but some steps can be taken to minimize its effects, such as changing the treatment regimen. Other measures that should be taken into account are quitting smoking (if applicable), oxygen therapy, pulmonary rehabilitation, vaccination against influenza and pneumococcus to prevent lung infections, or in extreme cases, a lung transplant.
The lungs are a radiosensitive organ, and radiation pneumonitis can occur leading to pulmonary insufficiency and death (100% after exposure to 50 gray of radiation) in a few months. Radiation pneumonitis is characterized by: Loss of epithelial cells; Edema; Inflammation; Occlusions airways, air sacs and blood vessels; Fibrosis
Radiation fibrosis, usually from the radiation given for cancer treatment. Certain drugs such as amiodarone, bleomycin and methotrexate. As a consequence of another disease such as rheumatoid arthritis. Hypersensitivity pneumonitis due to an allergic reaction to inhaled particles.
Treatment options for idiopathic pulmonary fibrosis are very limited, since no current treatment has stopped the progression of the disease. Because of this, there is no evidence that any medication can significantly help this condition, despite ongoing research trials.
Pulmonary toxicity is the medical name for side effects on the lungs. Although most cases of pulmonary toxicity in medicine are due to side effects of medicinal drugs, many cases can be due to side effects of radiation (radiotherapy). Other (non-medical) causes of pulmonary toxicity can be chemical compounds and airborne particulate matter.
Idiopathic pulmonary fibrosis is interstitial lung disease for which no obvious cause can be identified (idiopathic) and is associated with typical findings both radiographic (basal and pleural-based fibrosis with honeycombing) and pathologic (temporally and spatially heterogeneous fibrosis, histopathologic honeycombing, and fibroblastic foci).
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