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Common sites of metastasis for breast cancer. Metastatic breast cancer, also referred to as metastases, advanced breast cancer, secondary tumors, secondaries or stage IV breast cancer, is a stage of breast cancer where the breast cancer cells have spread to distant sites beyond the axillary lymph nodes. There is no cure for metastatic breast ...
Stage 4 is a metastatic cancer. Metastatic breast cancer has a less favorable prognosis. Receptor status. Cells have receptors on their surface and in their cytoplasm and nucleus. Chemical messengers such as hormones bind to receptors, and this causes changes in the cell.
This is an accepted version of this page This is the latest accepted revision, reviewed on 2 January 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical Oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...
Ericka Hart was 28 years old when she was diagnosed with bilateral breast cancer in May 2014. She received the fateful call from her doctor while walking around Wall Street in New York City, a ...
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
An MRI and subsequent ultrasound led to Munn's diagnosis of bilateral breast cancer, after luminal B, a rare and aggressive cancer, was found in both breasts, according to People.
Skin metastases most commonly extend to the skin overlying the mass, but may spread to the axilla or more distant areas. [18] Metastasis to adjacent lympatics may produce palpable masses in the axilla or an orange peel-like texture of the skin of the effected breast. [18] [19] Non-specific skin changes that may be signs of breast cancer.
If the tumor is diagnosed early, breast-saving surgery could be an option, although this is relatively uncommon. In non-metastatic MBC, the most common treatment is mastectomy. If the tumor is metastatic, surgery is no longer a viable option, and treatment generally defaults to aggressive chemotherapy.