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Commonly known as the blue lotus, Nymphaea Caerulea is available in several forms, including dried plant material, teas, and extracts for electronic cigarettes. The psychoactive effects of the flower are attributed to two aporphine alkaloids: apomorphine and nuciferine.
The half-life is 30–60 minutes, and the effects of the injection last for up to 90 minutes. [ 7 ] [ 8 ] [ 17 ] Toxicity depends on the route of administration; the LD 50 s in mice were 300 mg/kg for the oral route, 160 mg/kg for intraperitoneal , and 56 mg/kg intravenous.
These psychoactive effects make Nymphaea caerulea a likely candidate (among several) for the lotus plant eaten by the mythical Lotophagi in Homer's Odyssey. Used in aromatherapy, Nymphaea caerulea is purported to have a "divine" essence, bringing euphoria, heightened awareness and tranquility. [citation needed]
Nymphaea nouchali var. caerulea, [1] [a] is a water lily in the genus Nymphaea, a botanical variety of Nymphaea nouchali.. It is an aquatic plant of freshwater lakes, pools and rivers, naturally found throughout most of the eastern half of Africa, as well as parts of southern Arabia, but has also been spread to other regions as an ornamental plant.
List of psychoactive substances and precursor chemicals derived from genetically modified organisms; List of psychoactive substances derived from artificial fungi biotransformation; List of substances used in rituals; Medicinal fungi
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Nuciferine has been reported to have various anti-inflammatory effects, possibly mediated via PPAR delta activation. [4]According to a newer study from 2016, Nuciferine acts as an antagonist at 5-HT 2A, 5-HT 2C, and 5-HT 2B receptors, an inverse agonist at the 5-HT 7 receptor, a partial agonist at D2, D5, and 5-HT 6 receptors, and an agonist at 5-HT 1A and D4 receptors.
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