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The NBOMe drugs are highly potent and selective agonists of the serotonin 5-HT 2 receptors, including of the 5-HT 2A, 5-HT 2B, and 5-HT 2C receptors. [1] [3] [12] [13] However, they are much less potent and efficacious at the serotonin 5-HT 2B receptor compared to the serotonin 5-HT 2A and 5-HT 2C receptors. [3]
[2] [3] It can be viewed as benzaldehyde missing one hydrogen. The benzoyl group has a mass of 105 amu. The term "benzoyl" should not be confused with benzyl, which has the formula −CH 2 −C 6 H 5. The benzoyl group is given the symbol "Bz" whereas benzyl is commonly abbreviated "Bn".
2 di- 31 hentriaconta- 3 tri- 32 dotriaconta- 4 tetra- 33 tritriaconta- 5 penta- 34 tetratriaconta- 6 hexa- 40 tetraconta- 7 hepta- 50 pentaconta- 8 octa- 60 hexaconta- 9 nona- 70 heptaconta- 10 deca- 80 octaconta- 11 undeca- 90 nonaconta- 12 dodeca- 100 hecta- 13 trideca- 200 dicta- 14 tetradeca- 300 tricta- 15 pentadeca- 400 tetracta- 16
Benzonitrile is a useful solvent and a versatile precursor to many derivatives. It reacts with amines to afford N-substituted benzamides after hydrolysis. [3] It is a precursor to diphenylmethanimine via reaction with phenylmagnesium bromide followed by methanolysis.
Its affinity to other RGD-binding integrins is much lower (IC 50 for αvβ3, αvβ8, and α5β1 are 2.7, 6.2, and 22 nM, respectively; note that for IC 50, higher values mean lower affinity), [1] resulting in a high selectivity for αvβ6-integrin.
25CN-NBOH (sometimes also referred to as NBOH-2C-CN) [1] is a compound indirectly derived from the phenethylamine series of hallucinogens, which was discovered in 2014 at the University of Copenhagen. [2] It is a member of the NBOMe family of psychedelics. [3] The drug is notable in being selective agonists of the serotonin 5-HT 2A receptor ...
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1,2-Dimethoxybenzene 1,3-Dimethoxybenzene 1,4-Dimethoxybenzene Structural Formula: CAS Registry Number: 91-16-7 151-10-0 150-78-7