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The pons is also called the pons Varolii ("bridge of Varolius"), after the Italian anatomist and surgeon Costanzo Varolio (1543–75). [1] This region of the brainstem includes neural pathways and tracts that conduct signals from the brain down to the cerebellum and medulla, and tracts that carry the sensory signals up into the thalamus .
In 1573 he published this new method of dissecting the brain whereby he separated the brain from the skull and began the dissection from the base. Varolio described many of the brain's structures for the first time including the pons or pons Varolii which is a reflex center of respiration and a communication bridge between spinal cord and brain ...
The superior olivary complex (SOC) or superior olive is a collection of brainstem nuclei that is located in pons, functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system.
The brainstem (or brain stem) is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. [1] In the human brain the brainstem is composed of the midbrain , the pons , and the medulla oblongata . [ 1 ]
The blood–brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood. [1]
The pedunculopontine nucleus (PPN) or pedunculopontine tegmental nucleus (PPT or PPTg) is a collection of neurons located in the upper pons in the brainstem. [1] [2] It is involved in voluntary movements, [3] arousal, and provides sensory feedback to the cerebral cortex and one of the main components of the ascending reticular activating system.
The entire pathway begins and ends in the cerebral cortex, and its entire course is the following: [2] (Motor and sensory areas of) cerebral cortex → corticopontine fibers → (ipsilateral) nuclei pontis (synapse) → pontocerebellar fibers (decussation within pons) → middle cerebellar peduncle → (contralateral) (cerebellar cortex and (collaterals) dentate nucleus of) posterior lobe of ...
Long-chain fatty acids cannot cross the blood–brain barrier, but the liver can break these down to produce ketone bodies. However, short-chain fatty acids (e.g., butyric acid, propionic acid, and acetic acid) and the medium-chain fatty acids, octanoic acid and heptanoic acid, can cross the blood–brain barrier and be metabolised by brain cells.