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Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication) to decrease from its maximum concentration (C max) to half of C max in the blood plasma.
Half-life (symbol t ½) is the ... In biology and pharmacology. A biological half-life or elimination half-life is the time it takes for a substance (drug ...
Clearance, half-life and volume of distribution. There is an important relationship between clearance, elimination half-life and distribution volume.
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.It is intended as introductory material for novices; for more specific and technical definitions from sub-disciplines and related fields, see Glossary of cell biology, Glossary of genetics, Glossary of evolutionary biology, Glossary of ecology ...
The half-life of phosphorus-32 is 14.2 days, and its maximum specific activity is 9,131 kCi/mol (337.8 PBq/mol). Phosphorus-33 is used to label nucleotides. It is less energetic than phosphorus-32 and does not require protection with plexiglass.
In pharmacokinetics, the effective half-life is the rate of accumulation or elimination of a biochemical or pharmacological substance in an organism; it is the analogue of biological half-life when the kinetics are governed by multiple independent mechanisms.
11 C decays by positron emission with a half-life of ca. 20 min. 11 C is one of the isotopes often used in positron emission tomography. [3] 14 C decays by beta decay, with a half-life of 5730 years. It is continuously produced in the upper atmosphere of the earth, so it occurs at a trace level in the environment.
Half-life has units of time, and the elimination rate constant has units of 1/time, e.g., per hour or per day. An equation can be used to forecast the concentration of a compound at any future time when the fractional degration rate and steady state concentration are known: