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The SOLiD Sequencing System uses probes with dual base encoding. The underlying chemistry is summarized in the following steps: [12] - Step 1, Preparing a Library: This step begins with shearing the genomic DNA into small fragments. Then, two different adapters are added (for example A1 and A2).
It uses 2 base encoding to decode the raw data generated by the sequencing platform into sequence data. This method should not be confused with "sequencing by synthesis," a principle used by Roche-454 pyrosequencing (introduced in 2005, generating millions of 200-400bp reads in 2009), and the Solexa system (now owned by Illumina) (introduced in ...
DNA encoded chemical libraries (DECLs) are synthesized by the combinatorial chemistry principle and it clearly agrees with their application. [5] Fig. 1 DNA-encoded library displaying chemical compounds Schematic representation of DNA-encoded library displaying chemical compounds directly attached to oligonucleotides. a) Library generated by ...
The Simplified Molecular Input Line Entry System (SMILES) is a specification in the form of a line notation for describing the structure of chemical species using short ASCII strings. SMILES strings can be imported by most molecule editors for conversion back into two-dimensional drawings or three-dimensional models of the molecules.
A character encoding form (CEF) is the mapping of code points to code units to facilitate storage in a system that represents numbers as bit sequences of fixed length (i.e. practically any computer system). For example, a system that stores numeric information in 16-bit units can only directly represent code points 0 to 65,535 in each unit, but ...
The protocol of superdense coding has been actualized in several experiments using different systems to varying levels of channel capacity and fidelities. In 2004, trapped beryllium-9 ions were used in a maximally entangled state to achieve a channel capacity of 1.16 with a fidelity of 0.85. [ 5 ]
In chemistry, solid-phase synthesis is a method in which molecules are covalently bound on a solid support material and synthesised step-by-step in a single reaction vessel utilising selective protecting group chemistry. Benefits compared with normal synthesis in a liquid state include: High efficiency and throughput; Increased simplicity and speed
Unary coding, [nb 1] or the unary numeral system and also sometimes called thermometer code, is an entropy encoding that represents a natural number, n, with a code of length n + 1 ( or n), usually n ones followed by a zero (if natural number is understood as non-negative integer) or with n − 1 ones followed by a zero (if natural number is understood as strictly positive integer).