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Kidney damage is defined signs of damage seen in blood, urine, or imaging studies which includes lab albumin/creatinine ratio (ACR) ≥ 30. [59] All people with a GFR <60 mL/min/1.73 m 2 for 3 months are defined as having chronic kidney disease. [59]
The National Kidney Foundation notes that kidney disease can happen at any age but is more common in people over the age of 60. Research also shows that patients 70 and older are the fastest ...
Unlike chronic kidney disease, however, the kidneys can often recover from acute kidney injury, allowing the person with AKI to resume a normal life. People with acute kidney injury require supportive treatment until their kidneys recover function, and they often remain at increased risk of developing future kidney failure. [26]
[57] [needs update] Prednisone is usually prescribed at a dose of 60 mg/m 2 of body surface area/day in a first treatment for 4–8 weeks. After this period the dose is reduced to 40 mg/m 2 for a further 4 weeks. People experiencing a relapse or children are treated with prednisolone 2 mg/kg/day until urine becomes negative for protein.
For most patients, a GFR over 60 (mL/min)/(1.73 m 2) is adequate. But significant decline of the GFR from a previous test result can be an early indicator of kidney disease requiring medical intervention. The sooner kidney dysfunction is diagnosed and treated the greater odds of preserving remaining nephrons, and preventing the need for dialysis.
MeN is generally diagnosed in men in their twenties or thirties, and initially presents as a progressive decline in GFR without notable proteinuria. Traditional risk factors for CKD, including hypertension and diabetes mellitus, are generally absent. Despite international research efforts, the specific causes of the disease remain unknown ...
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It is more common in men (with a male-to-female ratio of up to 2:1). [2] It is most commonly diagnosed in the elderly (especially in people over 75 years of age). [3] Initial treatment is most commonly either partial or complete removal of the affected kidney(s). [4]