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Intramuscular injections began to be used for administration of vaccines for diphtheria in 1923, whooping cough in 1926, and tetanus in 1927. [30] By the 1970s, researchers and instructors began forming guidance on injection site and technique to reduce the risk of injection complications and side effects such as pain. [ 8 ]
In the movie Pulp Fiction, an intracardiac injection of epinephrine is used to treat a heroin overdose (far from the normal medical treatment for this condition, which would be an intravenous or intramuscular injection of naloxone). [4]
Adequate patient education and training on correct procedure for self-administration can lower the incidence rate of reactions. [2] Rotating injection sites, proper sterilization, and allowing the medication to reach room temperature before injection can help prevent ISRs. Applying a cold compress after the injection may be helpful. [2]
Intramuscular injections, abbreviated as IM, deliver a substance deep into a muscle, where they are quickly absorbed by the blood vessels into systemic circulation. Common injection sites include the deltoid , vastus lateralis , and ventrogluteal muscles. [ 9 ]
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Oral administration of a liquid. In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. [1] Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration ...