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With SSRIs, duration of treatment does not appear associated with the severity of withdrawal symptoms. [24] One hypothesis is that after the antidepressant is discontinued, there is a temporary (but in some cases long-lasting) deficiency in the brain of one or more essential neurotransmitters that regulate mood, such as serotonin, dopamine ...
SSRI use in pregnancy is associated with an increased risk of spontaneous abortion of about 1.7-fold. [ 141 ] [ 142 ] Use is also associated with preterm birth . [ 143 ] According to some researches, decreased body weight of the child, intrauterine growth retardation, neonatal adaptive syndrome, and persistent pulmonary hypertension also was noted.
Neonatal withdrawal or neonatal abstinence syndrome (NAS) or neonatal opioid withdrawal syndrome (NOWS) is a drug withdrawal syndrome of infants, caused by the cessation of the administration of drugs which may or may not be licit.
Antidepressant discontinuation syndrome, also called antidepressant withdrawal syndrome, is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication. [187] The symptoms may include flu-like symptoms, trouble sleeping, nausea, poor balance, sensory changes, and anxiety.
If your antidepressant isn’t working after several weeks or is causing side effects, you might not need to change to a new medication. Your healthcare provider may suggest a different dosage or ...
A 2018 analysis of 21 antidepressants found them to be fairly similar overall. [29] It found tentative evidence for mirtazapine being in the more effective group and middle in tolerability. [29] After one week of usage, mirtazapine was found to have an earlier onset of action compared to selective serotonin reuptake inhibitors. [24] [30]
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Generally, tapering is done is to avoid or minimize withdrawal symptoms that arise from neurobiological adaptation to the drug. [1] [2] Prescribed psychotropic drugs that may require tapering due to this physical dependence include opioids, [3] [4] [5] selective serotonin reuptake inhibitors, [6] antipsychotics, [7] anticonvulsants, [8] and ...